TCR β chain–directed bispecific antibodies for the treatment of T cell cancers

Immunotherapies such as chimeric antigen receptor (CAR) T cells and bispecific antibodies redirect healthy T cells to kill cancer cells expressing the target antigen. The pan-B cell antigen–targeting immunotherapies have been remarkably successful in treating B cell malignancies. Such therapies also...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Paul, Suman, Pearlman, Alexander H., Douglass, Jacqueline, Mog, Brian J., Hsiue, Emily Han-Chung, Hwang, Michael S., DiNapoli, Sarah R., Konig, Maximilian F., Brown, Patrick A., Wright, Katharine M., Sur, Surojit, Gabelli, Sandra B., Li, Yana, Ghiaur, Gabriel, Pardoll, Drew M., Papadopoulos, Nickolas, Bettegowda, Chetan, Kinzler, Kenneth W., Zhou, Shibin, Vogelstein, Bert
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236299/
https://ncbi.nlm.nih.gov/pubmed/33649188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.abd3595
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