Direct Detection and Quantification of Neo-antigens

Many immunotherapeutic approaches under development rely on T-cell recognition of cancer-derived peptides bound to human leukocyte antigen molecules on the cell surface. Direct experimental demonstration that such peptides are processed and bound is currently challenging. Here we described a method...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Wang, Qing, Douglass, Jacqueline, Hwang, Michael S., Hsiue, Emily Han-Chung, Mog, Brian J., Zhang, Ming, Papadopoulos, Nickolas, Kinzler, Kenneth W., Zhou, Shibin, Vogelstein, Bert
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825591/
https://ncbi.nlm.nih.gov/pubmed/31527070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0107
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