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Detection and quantification of rare mutations with massively parallel sequencing

The identification of mutations that are present in a small fraction of DNA templates is essential for progress in several areas of biomedical research. Although massively parallel sequencing instruments are in principle well suited to this task, the error rates in such instruments are generally too...

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Detaylı Bibliyografya
Asıl Yazarlar: Kinde, Isaac, Wu, Jian, Papadopoulos, Nick, Kinzler, Kenneth W., Vogelstein, Bert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111315/
https://ncbi.nlm.nih.gov/pubmed/21586637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105422108
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