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Detection and quantification of rare mutations with massively parallel sequencing
The identification of mutations that are present in a small fraction of DNA templates is essential for progress in several areas of biomedical research. Although massively parallel sequencing instruments are in principle well suited to this task, the error rates in such instruments are generally too...
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Asıl Yazarlar: | , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
National Academy of Sciences
2011
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111315/ https://ncbi.nlm.nih.gov/pubmed/21586637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105422108 |
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