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Remote loading of preencapsulated drugs into stealth liposomes

Loading drugs into carriers such as liposomes can increase the therapeutic ratio by reducing drug concentrations in normal tissues and raising their concentrations in tumors. Although this strategy has proven advantageous in certain circumstances, many drugs are highly hydrophobic and nonionizable a...

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Detalles Bibliográficos
Main Authors: Sur, Surojit, Fries, Anja C., Kinzler, Kenneth W., Zhou, Shibin, Vogelstein, Bert
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926059/
https://ncbi.nlm.nih.gov/pubmed/24474802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1324135111
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