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Remote loading of preencapsulated drugs into stealth liposomes

Loading drugs into carriers such as liposomes can increase the therapeutic ratio by reducing drug concentrations in normal tissues and raising their concentrations in tumors. Although this strategy has proven advantageous in certain circumstances, many drugs are highly hydrophobic and nonionizable a...

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書目詳細資料
Main Authors: Sur, Surojit, Fries, Anja C., Kinzler, Kenneth W., Zhou, Shibin, Vogelstein, Bert
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926059/
https://ncbi.nlm.nih.gov/pubmed/24474802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1324135111
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