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A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53
Through targeted homologous recombination, we developed a panel of matched colorectal cancer cell lines that differ only with respect to their endogenous TP53 status. We then used these lines to define the genes whose expression was altered after DNA damage induced by ionizing radiation. Transcripto...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2656188/ https://ncbi.nlm.nih.gov/pubmed/19225112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813333106 |
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