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Remote loading of preencapsulated drugs into stealth liposomes
Loading drugs into carriers such as liposomes can increase the therapeutic ratio by reducing drug concentrations in normal tissues and raising their concentrations in tumors. Although this strategy has proven advantageous in certain circumstances, many drugs are highly hydrophobic and nonionizable a...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926059/ https://ncbi.nlm.nih.gov/pubmed/24474802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1324135111 |
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