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Remote loading of preencapsulated drugs into stealth liposomes

Loading drugs into carriers such as liposomes can increase the therapeutic ratio by reducing drug concentrations in normal tissues and raising their concentrations in tumors. Although this strategy has proven advantageous in certain circumstances, many drugs are highly hydrophobic and nonionizable a...

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Detalhes bibliográficos
Main Authors: Sur, Surojit, Fries, Anja C., Kinzler, Kenneth W., Zhou, Shibin, Vogelstein, Bert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926059/
https://ncbi.nlm.nih.gov/pubmed/24474802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1324135111
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