Bispecific antibodies targeting mutant RAS neoantigens

Mutations in the RAS oncogenes occur in multiple cancers, and ways to target these mutations has been the subject of intense research for decades. Most of these efforts are focused on conventional small-molecule drugs rather than antibody-based therapies because the RAS proteins are intracellular. P...

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Detaylı Bibliyografya
Yayımlandı:Sci Immunol
Asıl Yazarlar: Douglass, Jacqueline, Hsiue, Emily Han-Chung, Mog, Brian J., Hwang, Michael S., DiNapoli, Sarah R., Pearlman, Alexander H., Miller, Michelle S., Wright, Katharine M., Azurmendi, P. Aitana, Wang, Qing, Paul, Suman, Schaefer, Annika, Skora, Andrew D., Molin, Marco Dal, Konig, Maximilian F., Liu, Qiang, Watson, Evangeline, Li, Yana, Murphy, Michael B., Pardoll, Drew M., Bettegowda, Chetan, Papadopoulos, Nickolas, Gabelli, Sandra B., Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141259/
https://ncbi.nlm.nih.gov/pubmed/33649101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abd5515
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