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The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome
Protein O-GlcNAcylation is a nutrient-related post-translational modification that, since its discovery some 30 years ago, has been associated with the development of neurodegenerative diseases. As reported in Alzheimer’s disease (AD), flaws in the cerebral glucose uptake translate into reduced hexo...
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| Vydáno v: | Neurotherapeutics |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer International Publishing
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8116370/ https://ncbi.nlm.nih.gov/pubmed/33258073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-020-00978-4 |
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