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The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome

Protein O-GlcNAcylation is a nutrient-related post-translational modification that, since its discovery some 30 years ago, has been associated with the development of neurodegenerative diseases. As reported in Alzheimer’s disease (AD), flaws in the cerebral glucose uptake translate into reduced hexo...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neurotherapeutics
Main Authors: Zuliani, Ilaria, Lanzillotta, Chiara, Tramutola, Antonella, Francioso, Antonio, Pagnotta, Sara, Barone, Eugenio, Perluigi, Marzia, Di Domenico, Fabio
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer International Publishing 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116370/
https://ncbi.nlm.nih.gov/pubmed/33258073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-020-00978-4
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