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Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors

Abnormal phosphorylation of tau has been considered as a key pathogenic mechanism inducing tau aggregation in multiple neurodegenerative disorders, collectively called tauopathies. Recent evidence showed that tau phosphorylation sites are protected with O-linked β-N-acetylglucosamine (O-GlcNAc) in n...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lim, Sungsu, Haque, Md. Mamunul, Nam, Ghilsoo, Ryoo, Nayeon, Rhim, Hyewhon, Kim, Yun Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613198/
https://ncbi.nlm.nih.gov/pubmed/26343633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160920212
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