Cell-based Models To Investigate Tau Aggregation

Accumulation of abnormal tau aggregates in neuron is an important pathological signature in multiple neurodegenerative disorders including Alzheimer's disease. Tau is a neuron specific microtubule-associated protein that regulates microtubule stability, which is critical for axonal outgrowth an...

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Bibliografiske detaljer
Udgivet i:Comput Struct Biotechnol J
Main Authors: Lim, Sungsu, Haque, Md. Mamunul, Kim, Dohee, Kim, Dong Jin, Kim, Yun Kyung
Format: Artigo
Sprog:Inglês
Udgivet: Research Network of Computational and Structural Biotechnology 2014
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262059/
https://ncbi.nlm.nih.gov/pubmed/25505502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2014.09.011
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