Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors

Abnormal phosphorylation of tau has been considered as a key pathogenic mechanism inducing tau aggregation in multiple neurodegenerative disorders, collectively called tauopathies. Recent evidence showed that tau phosphorylation sites are protected with O-linked β-N-acetylglucosamine (O-GlcNAc) in n...

Full description

Saved in:
Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Lim, Sungsu, Haque, Md. Mamunul, Nam, Ghilsoo, Ryoo, Nayeon, Rhim, Hyewhon, Kim, Yun Kyung
Format: Artigo
Language:Inglês
Published: MDPI 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613198/
https://ncbi.nlm.nih.gov/pubmed/26343633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160920212
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items