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Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors
Abnormal phosphorylation of tau has been considered as a key pathogenic mechanism inducing tau aggregation in multiple neurodegenerative disorders, collectively called tauopathies. Recent evidence showed that tau phosphorylation sites are protected with O-linked β-N-acetylglucosamine (O-GlcNAc) in n...
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| 發表在: | Int J Mol Sci |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613198/ https://ncbi.nlm.nih.gov/pubmed/26343633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160920212 |
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