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Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain
Down syndrome (DS) is the most frequent genetic cause of intellectual disability characterized by the presence of three copies of chromosome 21 (Chr21). Individuals with DS have sufficient neuropathology for a diagnosis of Alzheimer's disease (AD) after the age of 40 years. The aim of our study...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4062876/ https://ncbi.nlm.nih.gov/pubmed/24735980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.04.007 |
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