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Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain

Down syndrome (DS) is the most frequent genetic cause of intellectual disability characterized by the presence of three copies of chromosome 21 (Chr21). Individuals with DS have sufficient neuropathology for a diagnosis of Alzheimer's disease (AD) after the age of 40 years. The aim of our study...

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Bibliografiska uppgifter
Huvudupphovsmän:	Perluigi, Marzia, Pupo, Gilda, Tramutola, Antonella, Cini, Chiara, Coccia, Raffaella, Barone, Eugenio, Head, Elizabeth, Butterfield, D. Allan, Di Domenico, Fabio
Materialtyp:	Artigo
Språk:	Inglês
Publicerad:	2014
Ämnen:	Article
Länkar:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4062876/ https://ncbi.nlm.nih.gov/pubmed/24735980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.04.007
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Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain

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