Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain

Down syndrome (DS) is the most frequent genetic cause of intellectual disability characterized by the presence of three copies of chromosome 21 (Chr21). Individuals with DS have sufficient neuropathology for a diagnosis of Alzheimer's disease (AD) after the age of 40 years. The aim of our study...

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Main Authors: Perluigi, Marzia, Pupo, Gilda, Tramutola, Antonella, Cini, Chiara, Coccia, Raffaella, Barone, Eugenio, Head, Elizabeth, Butterfield, D. Allan, Di Domenico, Fabio
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062876/
https://ncbi.nlm.nih.gov/pubmed/24735980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.04.007
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