First-in-Human Assessment of (11)C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer

This was a first-in-human study of the PET radiotracer (11)C-LSN3172176 for the muscarinic acetylcholine receptor subtype M1. The objectives of the study were to determine the appropriate kinetic model to quantify binding of the tracer to M1 receptors, and the reliability of the chosen quantificatio...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Naganawa, Mika, Nabulsi, Nabeel, Henry, Shannan, Matuskey, David, Lin, Shu-Fei, Slieker, Lawrence, Schwarz, Adam J., Kant, Nancy, Jesudason, Cynthia, Ruley, Kevin, Navarro, Antonio, Gao, Hong, Ropchan, Jim, Labaree, David, Carson, Richard E., Huang, Yiyun
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2021
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049371/
https://ncbi.nlm.nih.gov/pubmed/32859711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.120.246967
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