First-in-Human Assessment of the Novel PDE2A PET Radiotracer (18)F-PF-05270430

This was a first-in-human study of the novel phosphodiesterase-2A (PDE2A) PET ligand (18)F-PF-05270430. The primary goals were to determine the appropriate tracer kinetic model to quantify brain uptake and to examine the within-subject test–retest variability. Methods: In advance of human studies, r...

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Bibliographic Details
Published in:J Nucl Med
Main Authors: Naganawa, Mika, Waterhouse, Rikki N., Nabulsi, Nabeel, Lin, Shu-Fei, Labaree, David, Ropchan, Jim, Tarabar, Sanela, DeMartinis, Nicholas, Ogden, Adam, Banerjee, Anindita, Huang, Yiyun, Carson, Richard E.
Format: Artigo
Language:Inglês
Published: Society of Nuclear Medicine 2016
Subjects:
Clinical Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093918/
https://ncbi.nlm.nih.gov/pubmed/27103022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.166850
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