First-in-Human Assessment of (11)C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer

This was a first-in-human study of the PET radiotracer (11)C-LSN3172176 for the muscarinic acetylcholine receptor subtype M1. The objectives of the study were to determine the appropriate kinetic model to quantify binding of the tracer to M1 receptors, and the reliability of the chosen quantificatio...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Nucl Med
Hlavní autoři: Naganawa, Mika, Nabulsi, Nabeel, Henry, Shannan, Matuskey, David, Lin, Shu-Fei, Slieker, Lawrence, Schwarz, Adam J., Kant, Nancy, Jesudason, Cynthia, Ruley, Kevin, Navarro, Antonio, Gao, Hong, Ropchan, Jim, Labaree, David, Carson, Richard E., Huang, Yiyun
Médium: Artigo
Jazyk:Inglês
Vydáno: Society of Nuclear Medicine 2021
Témata:
Neurology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049371/
https://ncbi.nlm.nih.gov/pubmed/32859711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.120.246967
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky