First-in-Human Assessment of (11)C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer

This was a first-in-human study of the PET radiotracer (11)C-LSN3172176 for the muscarinic acetylcholine receptor subtype M1. The objectives of the study were to determine the appropriate kinetic model to quantify binding of the tracer to M1 receptors, and the reliability of the chosen quantificatio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Nucl Med
Prif Awduron: Naganawa, Mika, Nabulsi, Nabeel, Henry, Shannan, Matuskey, David, Lin, Shu-Fei, Slieker, Lawrence, Schwarz, Adam J., Kant, Nancy, Jesudason, Cynthia, Ruley, Kevin, Navarro, Antonio, Gao, Hong, Ropchan, Jim, Labaree, David, Carson, Richard E., Huang, Yiyun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society of Nuclear Medicine 2021
Pynciau:
Neurology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049371/
https://ncbi.nlm.nih.gov/pubmed/32859711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.120.246967
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg