Binding of the synaptic vesicle radiotracer [(11)C]UCB-J is unchanged during functional brain activation using a visual stimulation task

The positron emission tomography radioligand [(11)C]UCB-J binds to synaptic vesicle glycoprotein 2 A (SV2A), a regulator of vesicle release. Increased neuronal firing could potentially affect tracer concentrations if binding site availability is altered during vesicle exocytosis. This study assessed...

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Bibliografische gegevens
Gepubliceerd in:J Cereb Blood Flow Metab
Hoofdauteurs: Smart, Kelly, Liu, Heather, Matuskey, David, Chen, Ming-Kai, Torres, Kristen, Nabulsi, Nabeel, Labaree, David, Ropchan, Jim, Hillmer, Ansel T, Huang, Yiyun, Carson, Richard E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2020
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054713/
https://ncbi.nlm.nih.gov/pubmed/32757741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X20946198
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