Region- and voxel-based quantification in human brain of [(18)F]LSN3316612, a radioligand for O-GlcNAcase

BACKGROUND: Previous studies found that the positron emission tomography (PET) radioligand [(18)F]LSN3316612 accurately quantified O-GlcNAcase in human brain using a two-tissue compartment model (2TCM). This study sought to assess kinetic model(s) as an alternative to 2TCM for quantifying [(18)F]LSN...

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Vydáno v:EJNMMI Res
Hlavní autoři: Lee, Jae-Hoon, Veronese, Mattia, Liow, Jeih-San, Morse, Cheryl L., Montero Santamaria, Jose A., Haskali, Mohammad B., Zoghbi, Sami S., Pike, Victor W., Innis, Robert B., Zanotti-Fregonara, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2021
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017047/
https://ncbi.nlm.nih.gov/pubmed/33796956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-021-00780-z
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