PET quantification of brain O-GlcNAcase with [(18)F]LSN3316612 in healthy human volunteers

BACKGROUND: Previous studies found that [(18)F]LSN3316612 was a promising positron emission tomography (PET) radioligand for imaging O-GlcNAcase in nonhuman primates and human volunteers. This study sought to further evaluate the suitability of [(18)F]LSN3316612 for human clinical research. METHODS:...

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Bibliografiske detaljer
Udgivet i:EJNMMI Res
Main Authors: Lee, Jae-Hoon, Liow, Jeih-San, Paul, Soumen, Morse, Cheryl L., Haskali, Mohammad B., Manly, Lester, Shcherbinin, Sergey, Ruble, J. Craig, Kant, Nancy, Collins, Emily C., Nuthall, Hugh N., Zanotti-Fregonara, Paolo, Zoghbi, Sami S., Pike, Victor W., Innis, Robert B.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072082/
https://ncbi.nlm.nih.gov/pubmed/32172476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-020-0616-4
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