O-GlcNAcase contributes to cognitive function in Drosophila

O-GlcNAcylation is an abundant post-translational modification in neurons. In mice, an increase in O-GlcNAcylation leads to defects in hippocampal synaptic plasticity and learning. O-GlcNAcylation is established by two opposing enzymes: O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). To investigat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Muha, Villo, Fenckova, Michaela, Ferenbach, Andrew T., Catinozzi, Marica, Eidhof, Ilse, Storkebaum, Erik, Schenck, Annette, van Aalten, Daan M. F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2020
Gaiak:
Glycobiology and Extracellular Matrices
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324509/
https://ncbi.nlm.nih.gov/pubmed/32094227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010312
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