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Drosophila O-GlcNAcase Deletion Globally Perturbs Chromatin O-GlcNAcylation

Gene expression during Drosophila development is subject to regulation by the Polycomb (Pc), Trithorax (Trx), and Compass chromatin modifier complexes. O-GlcNAc transferase (OGT/SXC) is essential for Pc repression suggesting that the O-GlcNAcylation of proteins plays a key role in regulating develop...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Akan, Ilhan, Love, Dona C., Harwood, Katryn R., Bond, Michelle R., Hanover, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858994/
https://ncbi.nlm.nih.gov/pubmed/26957542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704783
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