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Nuclear PTEN and p53 suppress stress-induced liver cancer through distinct mechanisms

PTEN and p53 are highly mutated in many cancers. These two tumor suppressors have critical functions in the nucleus, such as DNA repair, cell cycle progression, and genome maintenance. However, the in vivo functional relationship of nuclear PTEN and p53 is unknown. Here, we analyzed the liver of mic...

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Bibliografski detalji
Izdano u:Biochem Biophys Res Commun
Glavni autori: Kato, Takashi, Murata, Daisuke, Anders, Robert A., Sesaki, Hiromi, Iijima, Miho
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995232/
https://ncbi.nlm.nih.gov/pubmed/33667713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.02.093
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