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Nuclear PTEN and p53 suppress stress-induced liver cancer through distinct mechanisms

PTEN and p53 are highly mutated in many cancers. These two tumor suppressors have critical functions in the nucleus, such as DNA repair, cell cycle progression, and genome maintenance. However, the in vivo functional relationship of nuclear PTEN and p53 is unknown. Here, we analyzed the liver of mic...

詳細記述

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書誌詳細
出版年:Biochem Biophys Res Commun
主要な著者: Kato, Takashi, Murata, Daisuke, Anders, Robert A., Sesaki, Hiromi, Iijima, Miho
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995232/
https://ncbi.nlm.nih.gov/pubmed/33667713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.02.093
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