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Nuclear PTEN and p53 suppress stress-induced liver cancer through distinct mechanisms
PTEN and p53 are highly mutated in many cancers. These two tumor suppressors have critical functions in the nucleus, such as DNA repair, cell cycle progression, and genome maintenance. However, the in vivo functional relationship of nuclear PTEN and p53 is unknown. Here, we analyzed the liver of mic...
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| Publicado en: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7995232/ https://ncbi.nlm.nih.gov/pubmed/33667713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.02.093 |
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