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Nuclear PTEN Deficiency and Heterozygous PTEN Loss Have Distinct Impacts on Brain and Lymph Node Size
Defects in PTEN, a critical tumor suppressor, are associated with tumorigenesis and aberrant organ sizes. It has been shown that heterozygous PTEN loss increases brains and neuron size, while the specific loss of nuclear PTEN has the opposite effect. Here, we investigate the impact of a combination...
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| Pubblicato in: | Biochem Biophys Res Commun |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8085137/ https://ncbi.nlm.nih.gov/pubmed/33813280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.03.081 |
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