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Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities
The signaling lipid phosphatidylinositol (3,4,5)-trisphosphate (PIP3) is a key regulator of cell proliferation, survival, and migration and the enzyme that dephosphorylates it, phosphatase and tensin homolog (PTEN), is an important tumor suppressor. As excess PIP3 signaling is a hallmark of many can...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4084459/ https://ncbi.nlm.nih.gov/pubmed/24979808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409433111 |
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