Mechanism of Human PTEN Localization Revealed by Heterologous Expression in Dictyostelium

Phosphatase and tensin homolog (PTEN) is one of the most frequently mutated tumor suppressor genes in cancers. PTEN plays a central role in phosphatidylinositol (3,4,5)-trisphosphate (PIP3) signaling and converts PIP3 to phosphatidylinositol (4,5)-bisphosphate (PIP2) at the plasma membrane. Despite...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nguyen, Hoai-Nghia, Afkari, Yashar, Senoo, Hiroshi, Sesaki, Hiromi, Devreotes, Peter N., Iijima, Miho
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041858/
https://ncbi.nlm.nih.gov/pubmed/24292679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.507
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky