טוען...
Nuclear PTEN deficiency causes microcephaly with decreased neuronal soma size and increased seizure susceptibility
Defects in phosphatase and tensin homolog (PTEN) are associated with neurological disorders and tumors. PTEN functions at two primary intracellular locations: the plasma membrane and the nucleus. At the membrane, PTEN functions as a phosphatidylinositol (3,4,5)-trisphosphate phosphatase and suppress...
שמור ב:
| הוצא לאור ב: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6005449/ https://ncbi.nlm.nih.gov/pubmed/29735527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002356 |
| תגים: |
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