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Nuclear PTEN and p53 suppress stress-induced liver cancer through distinct mechanisms
PTEN and p53 are highly mutated in many cancers. These two tumor suppressors have critical functions in the nucleus, such as DNA repair, cell cycle progression, and genome maintenance. However, the in vivo functional relationship of nuclear PTEN and p53 is unknown. Here, we analyzed the liver of mic...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7995232/ https://ncbi.nlm.nih.gov/pubmed/33667713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.02.093 |
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