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Nuclear PTEN and p53 suppress stress-induced liver cancer through distinct mechanisms

PTEN and p53 are highly mutated in many cancers. These two tumor suppressors have critical functions in the nucleus, such as DNA repair, cell cycle progression, and genome maintenance. However, the in vivo functional relationship of nuclear PTEN and p53 is unknown. Here, we analyzed the liver of mic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biochem Biophys Res Commun
Päätekijät: Kato, Takashi, Murata, Daisuke, Anders, Robert A., Sesaki, Hiromi, Iijima, Miho
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995232/
https://ncbi.nlm.nih.gov/pubmed/33667713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.02.093
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