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Nuclear PTEN and p53 suppress stress-induced liver cancer through distinct mechanisms

PTEN and p53 are highly mutated in many cancers. These two tumor suppressors have critical functions in the nucleus, such as DNA repair, cell cycle progression, and genome maintenance. However, the in vivo functional relationship of nuclear PTEN and p53 is unknown. Here, we analyzed the liver of mic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochem Biophys Res Commun
Prif Awduron: Kato, Takashi, Murata, Daisuke, Anders, Robert A., Sesaki, Hiromi, Iijima, Miho
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995232/
https://ncbi.nlm.nih.gov/pubmed/33667713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.02.093
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