Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii

In animals, the response to chronic hypoxia is mediated by prolyl hydroxylases (PHDs) that regulate the levels of hypoxia-inducible transcription factor α (HIFα). PHD homologues exist in other types of eukaryotes and prokaryotes where they act on non HIF substrates. To gain insight into the factors...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Liu, Tongri, Abboud, Martine I., Chowdhury, Rasheduzzaman, Tumber, Anthony, Hardy, Adam P., Lippl, Kerstin, Lohans, Christopher T., Pires, Elisabete, Wickens, James, McDonough, Michael A., West, Christopher M., Schofield, Christopher J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2021
Pynciau:
Enzymology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864055/
https://ncbi.nlm.nih.gov/pubmed/32934009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013998
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