Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii

In animals, the response to chronic hypoxia is mediated by prolyl hydroxylases (PHDs) that regulate the levels of hypoxia-inducible transcription factor α (HIFα). PHD homologues exist in other types of eukaryotes and prokaryotes where they act on non HIF substrates. To gain insight into the factors...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Liu, Tongri, Abboud, Martine I., Chowdhury, Rasheduzzaman, Tumber, Anthony, Hardy, Adam P., Lippl, Kerstin, Lohans, Christopher T., Pires, Elisabete, Wickens, James, McDonough, Michael A., West, Christopher M., Schofield, Christopher J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2021
Gaiak:
Enzymology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864055/
https://ncbi.nlm.nih.gov/pubmed/32934009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013998
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