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Structural and functional characterization of engineered bifunctional fusion proteins of CD39 and CD73 ectonucleotidases
Extracellular diphosphate and triphosphate nucleotides are released from activated or injured cells to trigger vascular and immune P(2) purinergic receptors, provoking inflammation and vascular thrombosis. These metabokines are scavenged by ectonucleoside triphosphate diphosphohydrolase-1 (E-NTPDase...
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| 出版年: | Am J Physiol Cell Physiol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7846972/ https://ncbi.nlm.nih.gov/pubmed/33052071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00430.2020 |
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