Structural and functional characterization of engineered bifunctional fusion proteins of CD39 and CD73 ectonucleotidases

Extracellular diphosphate and triphosphate nucleotides are released from activated or injured cells to trigger vascular and immune P(2) purinergic receptors, provoking inflammation and vascular thrombosis. These metabokines are scavenged by ectonucleoside triphosphate diphosphohydrolase-1 (E-NTPDase...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Am J Physiol Cell Physiol
Autors principals: Zhong, Elizabeth H., Ledderose, Carola, De Andrade Mello, Paola, Enjyoji, Keiichi, Lunderberg, Justin Mark, Junger, Wolfgang, Robson, Simon C.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846972/
https://ncbi.nlm.nih.gov/pubmed/33052071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00430.2020
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars