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The ectonucleotidases CD39 and CD73: novel checkpoint inhibitor targets
Cancers are able to grow by subverting immune suppressive pathways, to prevent the malignant cells as being recognized as dangerous or foreign. This mechanism prevents the cancer from being eliminated by the immune system and allows disease to progress from a very early stage to a lethal state. Immu...
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| Publié dans: | Immunol Rev |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338647/ https://ncbi.nlm.nih.gov/pubmed/28258700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12528 |
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