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The ectonucleotidases CD39 and CD73: novel checkpoint inhibitor targets

Cancers are able to grow by subverting immune suppressive pathways, to prevent the malignant cells as being recognized as dangerous or foreign. This mechanism prevents the cancer from being eliminated by the immune system and allows disease to progress from a very early stage to a lethal state. Immu...

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Detalles Bibliográficos
Publicado en:Immunol Rev
Main Authors: Allard, Bertrand, Longhi, Maria Serena, Robson, Simon C., Stagg, John
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338647/
https://ncbi.nlm.nih.gov/pubmed/28258700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12528
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