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The ectonucleotidases CD39 and CD73: novel checkpoint inhibitor targets

Cancers are able to grow by subverting immune suppressive pathways, to prevent the malignant cells as being recognized as dangerous or foreign. This mechanism prevents the cancer from being eliminated by the immune system and allows disease to progress from a very early stage to a lethal state. Immu...

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Publicat a:Immunol Rev
Autors principals: Allard, Bertrand, Longhi, Maria Serena, Robson, Simon C., Stagg, John
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338647/
https://ncbi.nlm.nih.gov/pubmed/28258700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12528
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