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The Role of Ectonucleotidases CD39 and CD73 and Adenosine Signaling in Solid Organ Transplantation

Extracellular adenosine is a potent immunomodulatory molecule that accumulates in states of inflammation. Nucleotides such as adenosine triphosphate and adenosine diphosphate are release from injured and necrotic cells and hydrolyzed to adenosine monophosphate and adenosine by the concerted action o...

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Detalhes bibliográficos
Main Authors: Roberts, Veena, Stagg, John, Dwyer, Karen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927137/
https://ncbi.nlm.nih.gov/pubmed/24600452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00064
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