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The Role of Ectonucleotidases CD39 and CD73 and Adenosine Signaling in Solid Organ Transplantation

Extracellular adenosine is a potent immunomodulatory molecule that accumulates in states of inflammation. Nucleotides such as adenosine triphosphate and adenosine diphosphate are release from injured and necrotic cells and hydrolyzed to adenosine monophosphate and adenosine by the concerted action o...

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Autores principales: Roberts, Veena, Stagg, John, Dwyer, Karen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927137/
https://ncbi.nlm.nih.gov/pubmed/24600452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00064
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