Inhibition of neutrophils by hypertonic saline involves pannexin-1, CD39, CD73, and other ectonucleotidases

Hypertonic saline (HS) resuscitation has been studied as a possible strategy to reduce PMN activation and tissue damage in trauma patients. HS blocks PMNs by ATP release and stimulation of A2a adenosine receptors. Here we studied the underlying mechanisms in search of possible reasons for the incons...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Shock
Asıl Yazarlar: Chen, Yu, Bao, Yi, Zhang, Jingping, Woehrle, Tobias, Sumi, Yuka, Ledderose, Stephan, Li, Xiaoou, Ledderose, Carola, Junger, Wolfgang G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537693/
https://ncbi.nlm.nih.gov/pubmed/26009814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000402
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