A3 adenosine receptor inhibition improves the efficacy of hypertonic saline resuscitation

We reported previously that hypertonic saline (HS) treatment can prevent or upregulate the function of polymorphonuclear neutrophils (PMN) via A2a adenosine receptors (A2aR) or A3 adenosine receptors (A3R), respectively. A3R translocate to the cell surface upon PMN stimulation and thus HS promotes P...

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Bibliographic Details
Main Authors: Inoue, Yoshiaki, Tanaka, Hiroshi, Sumi, Yuka, Woehrle, Tobias, Chen, Yu, Hirsh, Mark I., Junger, Wolfgang G.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038630/
https://ncbi.nlm.nih.gov/pubmed/20661181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181f221fb
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