Hypertonic stress regulates T cell function via pannexin-1 hemichannels and P2X receptors

Hypertonic saline (HS) resuscitation increases T cell function and inhibits posttraumatic T cell anergy, which can reduce immunosuppression and sepsis in trauma patients. We have previously shown that HS induces the release of cellular ATP and enhances T cell function. However, the mechanism by whic...

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Detalhes bibliográficos
Main Authors: Woehrle, Tobias, Yip, Linda, Manohar, Monali, Sumi, Yuka, Yao, Yongli, Chen, Yu, Junger, Wolfgang G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2010
Assuntos:
Receptors, Signal Transduction, & Genes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996895/
https://ncbi.nlm.nih.gov/pubmed/20884646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0410211
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