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ATP release and autocrine signaling through P2X4 receptors regulate γδ T cell activation

Purinergic signaling plays a key role in a variety of physiological functions, including regulation of immune responses. Conventional αβ T cells release ATP upon TCR cross-linking; ATP binds to purinergic receptors expressed by these cells and triggers T cell activation in an autocrine and paracrine...

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Detalhes bibliográficos
Main Authors: Manohar, Monali, Hirsh, Mark I., Chen, Yu, Woehrle, Tobias, Karande, Anjali A., Junger, Wolfgang G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441317/
https://ncbi.nlm.nih.gov/pubmed/22753954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0312121
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