Cutting off the power: inhibition of leukemia cell growth by pausing basal ATP release and P2X receptor signaling?

T cells respond to antigen stimulation with the rapid release of cellular ATP, which stimulates an autocrine feedback mechanism that regulates calcium influx through P2X receptors. This autocrine purinergic feedback mechanism plays an essential role in the activation of T cells resulting in cell pro...

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Detalles Bibliográficos
Publicado en:Purinergic Signal
Autores principales: Ledderose, Carola, Woehrle, Tobias, Ledderose, Stephan, Strasser, Katharina, Seist, Richard, Bao, Yi, Zhang, Jingping, Junger, Wolfgang G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023625/
https://ncbi.nlm.nih.gov/pubmed/27020575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9510-y
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