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Mitochondria Are Gate-keepers of T Cell Function by Producing the ATP That Drives Purinergic Signaling
T cells play a central role in host defense. ATP release and autocrine feedback via purinergic receptors has been shown to regulate T cell function. However, the sources of the ATP that drives this process are not known. We found that stimulation of T cells triggers a spike in cellular ATP productio...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162192/ https://ncbi.nlm.nih.gov/pubmed/25070895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.575308 |
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