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Autocrine regulation of T-cell activation by ATP release and P2X(7) receptors

T-cell activation requires the influx of extracellular calcium, although mechanistic details regarding such activation are not fully defined. Here, we show that P2X(7) receptors play a key role in calcium influx and downstream signaling events associated with the activation of T cells. By real-time...

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Detalhes bibliográficos
Main Authors: Yip, Linda, Woehrle, Tobias, Corriden, Ross, Hirsh, Mark, Chen, Yu, Inoue, Yoshiaki, Ferrari, Vhe, Insel, Paul A., Junger, Wolfgang G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718802/
https://ncbi.nlm.nih.gov/pubmed/19211924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-126458
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