Pannexin-1 hemichannel–mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse

Engagement of T cells with antigen-presenting cells requires T-cell receptor (TCR) stimulation at the immune synapse. We previously reported that TCR stimulation induces the release of cellular adenosine-5′-triphosphate (ATP) that regulates T-cell activation. Here we tested the roles of pannexin-1 h...

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Detalhes bibliográficos
Main Authors: Woehrle, Tobias, Yip, Linda, Elkhal, Abdallah, Sumi, Yuka, Chen, Yu, Yao, Yongli, Insel, Paul A., Junger, Wolfgang G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981474/
https://ncbi.nlm.nih.gov/pubmed/20660288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-277707
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