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Hypertonic stress regulates T cell function via pannexin-1 hemichannels and P2X receptors

Hypertonic saline (HS) resuscitation increases T cell function and inhibits posttraumatic T cell anergy, which can reduce immunosuppression and sepsis in trauma patients. We have previously shown that HS induces the release of cellular ATP and enhances T cell function. However, the mechanism by whic...

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Autors principals: Woehrle, Tobias, Yip, Linda, Manohar, Monali, Sumi, Yuka, Yao, Yongli, Chen, Yu, Junger, Wolfgang G.
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996895/
https://ncbi.nlm.nih.gov/pubmed/20884646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0410211
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