Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases

T cells are involved in control of SARS-CoV-2 infection. To establish the patterns of immunodominance of different SARS-CoV-2 antigens, and precisely measure virus-specific CD4 (+) and CD8 (+) T cells, we studied epitope-specific T cell responses of approximately 100 convalescent COVID-19 cases. The...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Tarke, Alison, Sidney, John, Kidd, Conner K, Dan, Jennifer M., Ramirez, Sydney I., Yu, Esther Dawen, Mateus, Jose, da Silva Antunes, Ricardo, Moore, Erin, Rubiro, Paul, Methot, Nils, Phillips, Elizabeth, Mallal, Simon, Frazier, April, Rawlings, Stephen A., Greenbaum, Jason A., Peters, Bjoern, Smith, Davey M., Crotty, Shane, Weiskopf, Daniela, Grifoni, Alba, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743077/
https://ncbi.nlm.nih.gov/pubmed/33330869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.08.416750
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