Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

Many unknowns exist about human immune responses to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. SARS-CoV-2–reactive CD4(+) T cells have been reported in unexposed individuals, suggesting preexisting cross-reactive T cell memory in 20 to 50% of people. However, the source...

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Publicado no:Science
Main Authors: Mateus, Jose, Grifoni, Alba, Tarke, Alison, Sidney, John, Ramirez, Sydney I., Dan, Jennifer M., Burger, Zoe C., Rawlings, Stephen A., Smith, Davey M., Phillips, Elizabeth, Mallal, Simon, Lammers, Marshall, Rubiro, Paul, Quiambao, Lorenzo, Sutherland, Aaron, Yu, Esther Dawen, da Silva Antunes, Ricardo, Greenbaum, Jason, Frazier, April, Markmann, Alena J., Premkumar, Lakshmanane, de Silva, Aravinda, Peters, Bjoern, Crotty, Shane, Sette, Alessandro, Weiskopf, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574914/
https://ncbi.nlm.nih.gov/pubmed/32753554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd3871
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