Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

Understanding adaptive immunity to SARS-CoV-2 is important for vaccine development, interpreting coronavirus disease 2019 (COVID-19) pathogenesis, and calibration of pandemic control measures. Using HLA class I and II predicted peptide “megapools,” circulating SARS-CoV-2-specific CD8(+) and CD4(+) T...

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Publicado en:Cell
Autores principales: Grifoni, Alba, Weiskopf, Daniela, Ramirez, Sydney I., Mateus, Jose, Dan, Jennifer M., Moderbacher, Carolyn Rydyznski, Rawlings, Stephen A., Sutherland, Aaron, Premkumar, Lakshmanane, Jadi, Ramesh S., Marrama, Daniel, de Silva, Aravinda M., Frazier, April, Carlin, Aaron F., Greenbaum, Jason A., Peters, Bjoern, Krammer, Florian, Smith, Davey M., Crotty, Shane, Sette, Alessandro
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Inc. 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7237901/
https://ncbi.nlm.nih.gov/pubmed/32473127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.05.015
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